Megrelishvili R I, Glezer G A, Ryff I M, Sharov V G, Cherpachenko N M
Arkh Patol. 1978;40(5):53-60.
Under considerable physical load, marked enzymopathy, increased permeability of cellular membranes with the involvement of cellular and subcellular structures develop in the myocardium, skeletal musculature and viscera of rats. Administration of pyridozylate decreases the intensity of damage reactions and normalizes to a certain degree the structure of cellular and subcellular elements of tissues. This indicates the advisability of the employment of the cell respiration regulators under conditions of general and tissue hypoxy and metabolic shifts.
在相当大的体力负荷下，大鼠的心肌、骨骼肌和内脏中会出现明显的酶病，细胞膜通透性增加，并累及细胞和亚细胞结构。给予吡啶多酯可降低损伤反应的强度，并在一定程度上使组织的细胞和亚细胞成分结构正常化。这表明在全身和组织缺氧以及代谢变化的情况下使用细胞呼吸调节剂是可取的。
