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[肝硬化时小肠黏膜上皮细胞的超微结构变化]

[Ultrastructural changes in the epithelial cells of the small-intestinal mucosa in liver cirrhosis].

作者信息

Gerlovich E Sh, Reĭskanen A V, Iakhontova O I

出版信息

Arkh Patol. 1978;40(7):12-8.

PMID:687008
Abstract

Electron microscopic study of epithelial cells of cryptae and villi of the mucous membrane of the small intestine was carried out in 11 patients with portal cirrhosis of the liver in the active phase. Changes including a decrease in the number of ribosomes, impaired structure of mitochondria, microvilli, terminal reticulum, and glycocalix were found. Epithelial cells of the villi were affected more than the epithelium of cryptae. These changes were identical in the duodenum and in the proximal part of the jujunum.

摘要

对11例处于活动期的肝门脉性肝硬化患者的小肠黏膜隐窝和绒毛上皮细胞进行了电子显微镜研究。发现了包括核糖体数量减少、线粒体、微绒毛、终末网和糖萼结构受损等变化。绒毛的上皮细胞比隐窝的上皮受影响更大。十二指肠和空肠近端的这些变化是相同的。

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