Zannini G, Masciariello S, Pagano G, Sangiuolo P, Zotti G, Iaccarino V
Arch Surg. 1983 Aug;118(8):897-900. doi: 10.1001/archsurg.1983.01390080005001.
We studied 16 patients with hypersplenism, splenomegaly, and moderate nonbleeding portal hypertension with the purpose of discovering a hyperdynamic component associated with splenomegaly. We treated the patients' splenic hyperdynamic component and hypersplenism with a splenectomy. We measured wedge hepatic vein pressure (WHVP) before and after superior mesenteric artery occlusion by a balloon catheter, and after splenic artery (SA) occlusion by a balloon catheter. In 11 patients, following SA temporary occlusion an average WHVP reduction of 10.4 cm saline was obtained, and SA occlusion by Gianturco's coils was performed to obtain a gradual and segmentary occlusion. No colliquative phenomena were observed, and a stable decrease of WHVP with a marked improvement of peripheral cytopenia was obtained.
我们研究了16例患有脾功能亢进、脾肿大和中度非出血性门静脉高压的患者，目的是发现与脾肿大相关的高动力成分。我们通过脾切除术治疗患者的脾高动力成分和脾功能亢进。我们用球囊导管测量了肠系膜上动脉闭塞前后以及脾动脉（SA）闭塞后的肝静脉楔压（WHVP）。11例患者在SA暂时闭塞后，平均WHVP降低了10.4 cm盐水柱，随后用Gianturco弹簧圈进行SA闭塞以实现逐步节段性闭塞。未观察到液化现象，WHVP持续下降，外周血细胞减少明显改善。
