Lillemoe K D, Brigham R A, Harmon J W, Feaster M M, Saunders J R, d'Avis J A
Arch Surg. 1983 Aug;118(8):905-7. doi: 10.1001/archsurg.1983.01390080013004.
We treated 17 patients with severe small-bowel radiation enteritis surgically. Fourteen patients were female. Gynecologic malignant lesions (cervical, ovarian, and endometrial) were the most frequent sites of the primary tumors for which radiation was given. Thirteen patients had bowel obstruction, and the remainder had enterovaginal fistulae. Intestinal bypass, rather than resection, was the preferred approach in the treatment of these patients, and was used in 11 cases. Successful palliation was provided in nine patients, with minimal morbidity and no operative deaths. Follow-up at eight to 60 months has shown no further sequelae of radiation injury or of blind loop syndrome. This supports the relative safety of intestinal bypass for the surgical management of small-bowel radiation enteritis.
我们对17例严重小肠放射性肠炎患者进行了手术治疗。14例为女性。妇科恶性病变(宫颈癌、卵巢癌和子宫内膜癌)是接受放疗的原发性肿瘤最常见的部位。13例患者出现肠梗阻,其余患者有肠阴道瘘。在这些患者的治疗中,肠道转流术而非切除术是首选方法,11例采用了该方法。9例患者获得了成功的姑息治疗,发病率极低且无手术死亡。8至60个月的随访显示,未出现放射性损伤或盲袢综合征的进一步后遗症。这支持了肠道转流术用于小肠放射性肠炎手术治疗的相对安全性。