Weinberger J, Robbins A
Arch Neurol. 1983 Aug;40(8):489-92. doi: 10.1001/archneur.1983.04210070029009.
Real-time B-mode ultrasonography was employed to image nonobstructive atherosclerotic plaque formation in the carotid artery bifurcation. Hemodynamic factors were assessed by pneumo-oculoplethsymography and Doppler flow study. Hemodynamically obstructive lesions were associated with a significantly higher incidence of cerebral ischemic symptoms than were nonobstructive plaques. Two types of nonobstructive plaques were delineated: isolated nodular plaques and mural plaques along the wall of the carotid sinus. Nodular plaques were associated with significantly fewer ischemic symptoms and strokes than were obstructive lesions. Mural plaques also had a lower incidence of symptoms than obstructive lesions, but the difference was not significant. Noninvasive determination of the morphologic and physiologic characteristics of atherosclerotic lesions at the carotid bifurcation can be of considerable value in the management of patients with transient ischemic attacks.
采用实时B型超声成像技术观察颈动脉分叉处非阻塞性动脉粥样硬化斑块的形成。通过气眼体积描记法和多普勒血流研究评估血流动力学因素。与非阻塞性斑块相比，血流动力学阻塞性病变与脑缺血症状的发生率显著更高相关。确定了两种类型的非阻塞性斑块：孤立的结节状斑块和沿颈动脉窦壁的壁状斑块。与阻塞性病变相比，结节状斑块与缺血症状和中风的发生率显著更低相关。壁状斑块的症状发生率也低于阻塞性病变，但差异不显著。无创测定颈动脉分叉处动脉粥样硬化病变的形态学和生理学特征对短暂性脑缺血发作患者的管理具有重要价值。
