Anderson D C, Loewenson R, Yock D, Farber R, Larson D, Bromer M
Arch Neurol. 1983 Aug;40(8):484-8. doi: 10.1001/archneur.1983.04210070024008.
B-mode, real-time ultrasonic imaging was prospectively evaluated as a screening test for atherosclerotic occlusive vascular disease in the carotid bifurcation region, as defined by carotid angiography in 100 carotid systems in 50 patients. Preliminary reliability studies for each technique assessed agreement between examiners. Sensitivities of ultrasonography for stenosis greater than 50% of luminal diameter, complicated plaque ulceration, complete occlusion, and "surgical disease" by any of these parameters were 79%, 26%, 25%, and 73%, respectively. Thirty-seven percent of the 100 carotid systems were found to contain surgically relevant disease by angiography, compared with 19% and 56%, respectively, of the carotid systems with negative and positive ultrasonographic results. Judicious use of ultrasonography as a screen for angiography requires awareness of these limitations.
对50例患者的100个颈动脉系统进行颈动脉血管造影，以此定义颈动脉分叉区域的动脉粥样硬化闭塞性血管疾病，并将B型实时超声成像作为一种筛查试验进行前瞻性评估。对每种技术的初步可靠性研究评估了检查者之间的一致性。超声检查对管腔直径狭窄大于50%、复杂斑块溃疡、完全闭塞以及任何这些参数定义的“手术疾病”的敏感性分别为79%、26%、25%和73%。血管造影显示，100个颈动脉系统中有37%存在与手术相关的疾病，相比之下，超声检查结果为阴性和阳性的颈动脉系统中，这一比例分别为19%和56%。明智地使用超声检查作为血管造影的筛查手段需要了解这些局限性。
