Acetylation of puromycin by Streptomyces alboniger the producing organism.
作者信息
Pérez-González J A, Vara J, Jiménez A
出版信息
Biochem Biophys Res Commun. 1983 Jun 29;113(3):772-7. doi: 10.1016/0006-291x(83)91066-5.
PMID:6870889
Abstract
Streptomyces alboniger produces the antibiotic puromycin and expresses an enzymic activity which acetylates the drug using acetyl CoA. The N-acetyl-puromycin formed is biologically inactive against protein synthesis in Bacillus subtilis (as assayed in vivo).
摘要
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