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采用心内膜垫人工瓣膜对完全性房室通道缺损进行手术治疗。

Surgical treatment of complete atrioventricular canal defect with an endocardial cushion prosthesis.

作者信息

Kawashima Y, Matsuda H, Hirose H, Nakano S, Shimazaki Y, Miyamoto K

出版信息

Circulation. 1983 Sep;68(3 Pt 2):II139-43.

PMID:6872184
Abstract

In order to obtain better operative results with less postoperative atrioventricular valve regurgitation, we have developed a new method of repair for the complete atrioventricular canal with a composite prosthetic patch called an endocardial cushion prosthesis, in which horizontal wings are attached to a vertical patch on both sides to compensate for the defective atrioventricular valve tissue. Ten patients ranging in age from 8 months to 8 years (mean 28.9 months) have been operated on with this technique since 1975. All patients except one showed severe preoperative pulmonary hypertension (over 50 mm Hg) in mean pulmonary artery pressure. Six patients had trivial-to-moderate mitral regurgitation before surgery. Nine patients survived the operation (operative mortality 10%). Postoperative mitral regurgitation was found in three of seven patients who underwent cardiac catheterization and angiocardiographic examination at an average of 4.4 months after surgery. The grades of mitral regurgitation were trivial in all. Mild-to-moderate tricuspid regurgitation was observed in five patients and there was a correlation between the grades of tricuspid regurgitation and pulmonary/systemic peak pressure ratio (r = .757, p less than .05). This method appears to be advantageous in preventing postoperative mitral regurgitation with low operative mortality. However, tricuspid regurgitation was not well avoided among the patients with persisting pulmonary hypertension.

摘要

为了获得更好的手术效果并减少术后房室瓣反流,我们开发了一种新的完全性房室通道修补方法,使用一种称为心内膜垫假体的复合人工补片,其中水平翼附着在垂直补片的两侧,以补偿有缺陷的房室瓣组织。自1975年以来,已有10例年龄在8个月至8岁(平均28.9个月)的患者接受了这项技术的手术。除1例患者外,所有患者术前均表现为严重肺动脉高压(平均肺动脉压超过50mmHg)。6例患者术前有轻度至中度二尖瓣反流。9例患者术后存活(手术死亡率10%)。在术后平均4.4个月接受心导管检查和心血管造影检查的7例患者中,有3例发现术后二尖瓣反流。所有患者的二尖瓣反流程度均为轻度。5例患者观察到轻度至中度三尖瓣反流,三尖瓣反流程度与肺/体循环峰值压力比之间存在相关性(r = 0.757,p < 0.05)。这种方法在预防术后二尖瓣反流方面似乎具有优势,手术死亡率较低。然而,在持续存在肺动脉高压的患者中,三尖瓣反流未能得到很好的避免。

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