• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Chronic clozapine treatment of rats down-regulates cortical 5-HT2 receptors.

作者信息

Reynolds G P, Garrett N J, Rupniak N, Jenner P, Marsden C D

出版信息

Eur J Pharmacol. 1983 May 6;89(3-4):325-6. doi: 10.1016/0014-2999(83)90517-4.

DOI:10.1016/0014-2999(83)90517-4
PMID:6873168
Abstract
摘要

相似文献

1
Chronic clozapine treatment of rats down-regulates cortical 5-HT2 receptors.
Eur J Pharmacol. 1983 May 6;89(3-4):325-6. doi: 10.1016/0014-2999(83)90517-4.
2
Effects of clozapine and other neuroleptics on binding of [3H]-Q ICS 205-930 to central 5-HT3 recognition sites.
Br J Pharmacol. 1989 Dec;98 Suppl:813P.
3
Effects of acute and chronic treatments with clozapine and haloperidol on serotonin (5-HT2) and dopamine (D2) receptors in the rat brain.氯氮平和氟哌啶醇急性及慢性治疗对大鼠脑内5-羟色胺（5-HT2）和多巴胺（D2）受体的影响
Brain Res. 1989 May 22;487(2):288-98. doi: 10.1016/0006-8993(89)90833-0.
4
Effect of typical and atypical antipsychotic drugs on 5-HT2 receptor density in rat cerebral cortex.典型和非典型抗精神病药物对大鼠大脑皮质5-羟色胺2受体密度的影响。
Life Sci. 1989;45(15):1397-406. doi: 10.1016/0024-3205(89)90027-1.
5
The effect of typical and atypical antipsychotic drugs on the stimulation of phosphoinositide hydrolysis produced by the 5-HT3 receptor agonist 2-methyl-serotonin.
Brain Res. 1991 Apr 5;545(1-2):276-8. doi: 10.1016/0006-8993(91)91296-d.
6
Effects of antipsychotic drugs on 5-HT2 receptors in the medial prefrontal cortex: microiontophoretic studies.
Brain Res. 1990 Jan 8;506(2):346-8. doi: 10.1016/0006-8993(90)91278-o.
7
Changes in cortical 5-HT2 receptors following 5-HTP and paroxetine administration in rats.大鼠给予5-羟色氨酸（5-HTP）和帕罗西汀后皮质5-羟色胺2（5-HT2）受体的变化
J Nihon Univ Sch Dent. 1988 Sep;30(3):218-26. doi: 10.2334/josnusd1959.30.218.
8
Regulation of 5-HT2 receptors in rat cortex. Studies with a putative selective agonist and an antagonist.
Biochem Pharmacol. 1991 Aug 8;42(5):1099-105. doi: 10.1016/0006-2952(91)90294-f.
9
Acetylcholine synthesis in rat brain: dissimilar effects of clozapine and chlorpromazine.大鼠脑中乙酰胆碱的合成：氯氮平和氯丙嗪的不同作用
Life Sci. 1975 Sep 1;17(5):739-47. doi: 10.1016/0024-3205(75)90529-9.
10
The effects of clozapine and fluperlapine on the in vivo release and metabolism of dopamine in the striatum and in the prefrontal cortex of freely moving rats.
Psychopharmacol Bull. 1989;25(3):383-9.

引用本文的文献

1
Serotonin receptors represent highly favorable molecular targets for cognitive enhancement in schizophrenia and other disorders.血清素受体是精神分裂症和其他疾病中认知增强的高度有利分子靶点。
Psychopharmacology (Berl). 2004 Jun;174(1):17-24. doi: 10.1007/s00213-003-1683-8. Epub 2003 Dec 2.
2
Differential region-specific regulation of central alpha 1-adrenoceptor binding following chronic haloperidol and clozapine administration in the rat.大鼠长期服用氟哌啶醇和氯氮平后中枢α1-肾上腺素能受体结合的区域特异性差异调节
Psychopharmacology (Berl). 2004 Mar;172(2):196-201. doi: 10.1007/s00213-003-1639-z. Epub 2003 Oct 8.
3
Mechanisms of action of atypical antipsychotic drugs: a critical analysis.
非典型抗精神病药物的作用机制：批判性分析
Psychopharmacology (Berl). 1996 Mar;124(1-2):2-34. doi: 10.1007/BF02245602.
4
The effects of manipulation of presynaptic 5-HT nerve terminals on postsynaptic 5-HT1 and 5-HT2 binding sites of the rat brain.操纵大鼠脑内突触前5-羟色胺（5-HT）神经末梢对突触后5-HT1和5-HT2结合位点的影响。
J Neural Transm. 1985;64(2):129-43. doi: 10.1007/BF01245974.
5
Inhibition of head twitch response to quipazine in rats by chronic amitriptyline but not fluvoxamine or citalopram.慢性给予阿米替林可抑制大鼠对喹哌嗪的头部抽搐反应，而氟伏沙明或西酞普兰则无此作用。
Psychopharmacology (Berl). 1986;88(3):279-84. doi: 10.1007/BF00180825.
6
Clozapine: new research on efficacy and mechanism of action.氯氮平：疗效与作用机制的新研究
Eur Arch Psychiatry Neurol Sci. 1989;238(5-6):332-9. doi: 10.1007/BF00449814.
7
Clozapine. A review of its pharmacological properties, and therapeutic use in schizophrenia.氯氮平：其药理特性及在精神分裂症治疗中的应用综述
Drugs. 1990 Nov;40(5):722-47. doi: 10.2165/00003495-199040050-00007.