Agarwal R K, Agarwal S M
Experientia. 1983 Aug 15;39(8):905-6. doi: 10.1007/BF01990430.
White leghorn chickens, when infected with repeated doses of Ancylostoma caninum larvae, expel the larvae at a faster rate than when infected with a single dose. This suggests that the initial dose induces some resistance in the host. An initial dose of 1000 and 2000 larvae, followed by a 2nd dose of the same order, induces resistance in the alimentary tract causing the entire larval burden either to migrate to other tissues (organs) or to be expelled in 24 h.
白来航鸡在反复感染犬钩虫幼虫时,比单次感染时排出幼虫的速度更快。这表明初始剂量会在宿主体内诱导某种抗性。初始剂量为1000和2000条幼虫,随后给予相同数量级的第二剂,会在消化道诱导抗性,使全部幼虫负荷要么迁移到其他组织(器官),要么在24小时内被排出。