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从人腮腺唾液富含脯氨酸的碱性糖蛋白中获得的糖肽的氨基酸序列。

Amino acid sequences of glycopeptides obtained from basic proline-rich glycoprotein of human parotid saliva.

作者信息

Shimomura H, Kanai Y, Sanada K

出版信息

J Biochem. 1983 Mar;93(3):857-63. doi: 10.1093/jb/93.3.857.

DOI:10.1093/jb/93.3.857
PMID:6874667
Abstract

A proline-rich glycoprotein, in which proline, glutamic acid, and glycine represent about 80 per cent of the total residues, was obtained from human parotid saliva. The amino acid sequences of glycopeptides obtained from digests of the glycoprotein with clostripain were determined to be Pro-Gly-Lys-Pro-Glu-Gly-Pro-Pro-Pro-Gln-Gly-Gly-Asn(CHO)-Gln-Ser-Gln-Gly-Pro- Pro-Pro-Arg and Pro-Pro-Gln-Gly-Gly-Asn(CHO)-Gln-Ser-Gln-Gly-Pro-Pro-Pro-His-Pro-Gly-Lys-Pro -Glu-Arg. The structural relationship between the glycopeptides and the known salivary peptide is discussed.

摘要

从人腮腺唾液中获得了一种富含脯氨酸的糖蛋白，其中脯氨酸、谷氨酸和甘氨酸约占总残基的80%。用梭菌蛋白酶消化该糖蛋白得到的糖肽的氨基酸序列被确定为Pro-Gly-Lys-Pro-Glu-Gly-Pro-Pro-Pro-Gln-Gly-Gly-Asn(CHO)-Gln-Ser-Gln-Gly-Pro-Pro-Pro-Arg和Pro-Pro-Gln-Gly-Gly-Asn(CHO)-Gln-Ser-Gln-Gly-Pro-Pro-Pro-His-Pro-Gly-Lys-Pro-Glu-Arg。讨论了这些糖肽与已知唾液肽之间的结构关系。

相似文献

1
Amino acid sequences of glycopeptides obtained from basic proline-rich glycoprotein of human parotid saliva.从人腮腺唾液富含脯氨酸的碱性糖蛋白中获得的糖肽的氨基酸序列。
J Biochem. 1983 Mar;93(3):857-63. doi: 10.1093/jb/93.3.857.
2
Further fractionation of basic proline-rich peptides from human parotid saliva and complete amino acid sequence of basic proline-rich peptide P-H.人腮腺唾液中富含脯氨酸的碱性肽的进一步分级分离及富含脯氨酸的碱性肽P-H的完整氨基酸序列
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Complete amino acid sequence of a basic proline-rich peptide, P-D, from human parotid saliva.来自人腮腺唾液的富含脯氨酸的碱性肽P-D的完整氨基酸序列。
J Biochem. 1983 Feb;93(2):495-502. doi: 10.1093/oxfordjournals.jbchem.a134204.

引用本文的文献

1
PRB1, PRB2, and PRB4 coded polymorphisms among human salivary concanavalin-A binding, II-1, and Po proline-rich proteins.人唾液伴刀豆球蛋白A结合蛋白、II-1蛋白和富含脯氨酸的Po蛋白中的PRB1、PRB2和PRB4编码多态性。
Am J Hum Genet. 1996 Jan;58(1):143-53.
2
Clones from the human gene complex coding for salivary proline-rich proteins.编码富含脯氨酸唾液蛋白的人类基因复合体的克隆。
Proc Natl Acad Sci U S A. 1984 Sep;81(17):5561-5. doi: 10.1073/pnas.81.17.5561.
3
Nuclear magnetic resonance spectroscopic and computer-stimulated structural analyses of a heptapeptide sequence found around the N-glycosylation site of a proline-rich glycoprotein from human parotid saliva.
对来自人腮腺唾液富含脯氨酸糖蛋白N-糖基化位点周围发现的七肽序列进行核磁共振光谱分析和计算机模拟结构分析。
Biophys J. 1987 Feb;51(2):193-203. doi: 10.1016/S0006-3495(87)83325-8.
4
Use of the photoaffinity cross-linking agent N-hydroxysuccinimidyl-4-azidosalicylic acid to characterize salivary-glycoprotein-bacterial interactions.使用光亲和交联剂N-羟基琥珀酰亚胺基-4-叠氮基水杨酸来表征唾液糖蛋白与细菌的相互作用。
Biochem J. 1986 Feb 15;234(1):43-8. doi: 10.1042/bj2340043.
5
Many protein products from a few loci: assignment of human salivary proline-rich proteins to specific loci.少数基因座产生多种蛋白质产物：人类唾液富含脯氨酸蛋白在特定基因座上的定位
Genetics. 1988 Sep;120(1):255-65. doi: 10.1093/genetics/120.1.255.
6
Human salivary proline-rich protein genes on chromosome 12.位于12号染色体上的人类唾液富含脯氨酸蛋白基因。
Am J Hum Genet. 1985 Mar;37(2):418-24.
7
Alleles at the PRB3 locus coding for a disulfide-bonded human salivary proline-rich glycoprotein (Gl 8) and a null in an Ashkenazi Jew.PRB3基因座上的等位基因编码一种二硫键连接的富含脯氨酸的人唾液糖蛋白（Gl 8），在一名阿什肯纳兹犹太人中存在一个无效等位基因。
Am J Hum Genet. 1990 Oct;47(4):686-97.