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一种富含脯氨酸的唾液肽P-C的氨基酸序列及其与一种富含脯氨酸的唾液磷蛋白C蛋白的关系。

The amino acid sequence of a salivary proline-rich peptide, P-C, and its relation to a salivary proline-rich phosphoprotein, protein C.

作者信息

Isemura S, Saitoh E, Sanada K

出版信息

J Biochem. 1980 Apr;87(4):1071-7.

PMID:7390979
Abstract

A basic proline-rich peptide, P-C, was isolated from human whole saliva and its amino acid sequence was determined to be Gly-Arg-Pro-Gln-Gly-Pro-Pro-Gln-Gln-Gly-Gly-His-Gln-Gln-Gly-Pro-Pro-Pro-Pro-Pro-Pro-Gly-Lys-Pro-Gln-Gly-Pro-Pro-Pro-Gln-Gly-Gly-Arg-Pro-Gln-Gly-Pro-Pro-Gln-Gly-Gln-Ser-Pro-Gln. P-C was also found to be present in stimulated parotid saliva. The sequence determined appears to correspond to the C-terminal 44 residues of a proline-rich phosphoprotein, Protein C, the partial sequence of which has been elucidated, and suggests that P-C might be derived from Protein C.

摘要

一种富含脯氨酸的碱性肽P-C从人全唾液中分离出来，其氨基酸序列确定为甘氨酸-精氨酸-脯氨酸-谷氨酰胺-甘氨酸-脯氨酸-脯氨酸-谷氨酰胺-谷氨酰胺-甘氨酸-甘氨酸-组氨酸-谷氨酰胺-谷氨酰胺-甘氨酸-脯氨酸-脯氨酸-脯氨酸-脯氨酸-脯氨酸-脯氨酸-甘氨酸-赖氨酸-脯氨酸-谷氨酰胺-甘氨酸-脯氨酸-脯氨酸-脯氨酸-谷氨酰胺-甘氨酸-甘氨酸-精氨酸-脯氨酸-谷氨酰胺-甘氨酸-脯氨酸-脯氨酸-谷氨酰胺-甘氨酸-谷氨酰胺-丝氨酸-脯氨酸-谷氨酰胺。还发现P-C存在于刺激性腮腺唾液中。所确定的序列似乎对应于一种富含脯氨酸的磷蛋白C蛋白的C末端44个残基，其部分序列已得到阐明，这表明P-C可能来源于C蛋白。

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引用本文的文献

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