Estafanous F G, Tarazi R C, Buckley S, Taylor P C
Br Heart J. 1978 Jul;40(7):718-24. doi: 10.1136/hrt.40.7.718.
Paroxysmal hypertension occurred during the first 8 hours after cardiac valve replacement in 15 of 186 consecutive patients. The clinical characteristics of this hypertension were similar to those of hypertension after myocardial revascularization, except that this complication occurred much less frequently after valve replacement (8.1%) than after myocardial revascularisation (33%) (P less than 0.001). Hypertension resulting from hypoxia, hypercapnia, shivering, or arousal from anaesthesia was excluded from consideration. The rise in systemic arterial pressure (average 34/35 mmHg +/- 4.9/4.3 SE) was usually associated with a reduction in central venous pressure (12/15 patients) and a mild increase (2 to 4 cm saline) in left atrial pressure. The incidence of hypertension was not related to the valve replaced (aortic or mitral), type of lesion (stenosis or regurgitation), preoperative level of blood pressure, or use of hypothermia during operation. However, none of the 18 patients who had double valve replacement showed significant rise in blood pressure after operation. It is suggested that these hypertensive episodes may be related to pressor reflexes from the heart and/or great vessels.
在连续186例心脏瓣膜置换术后的最初8小时内,15例患者出现阵发性高血压。这种高血压的临床特征与心肌血运重建术后的高血压相似,只是该并发症在瓣膜置换术后的发生率(8.1%)远低于心肌血运重建术后(33%)(P<0.001)。因缺氧、高碳酸血症、寒战或麻醉苏醒引起的高血压被排除在外。体循环动脉压升高(平均34/35 mmHg±4.9/4.3 SE)通常伴有中心静脉压降低(12/15例患者)和左心房压轻度升高(2至4 cm盐水柱)。高血压的发生率与置换的瓣膜(主动脉瓣或二尖瓣)、病变类型(狭窄或反流)、术前血压水平或手术期间是否使用低温无关。然而,18例接受双瓣膜置换的患者术后均未出现明显的血压升高。提示这些高血压发作可能与心脏和/或大血管的升压反射有关。