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[宫颈癌群体筛查适宜间隔时间的研究]

[Studies on the appropriated interval of mass screening for cervical cancer].

作者信息

Kusanagi T, Kudo R, Ito E, Sagae S, Hori Y, Tamura H, Hayakawa O, Fujimura Y, Hashimoto M

出版信息

Nihon Sanka Fujinka Gakkai Zasshi. 1983 Jun;35(6):782-6.

PMID:6875333
Abstract

In order to study the appropriate interval for cervical cancer screening, we investigated mainly the screening history of 1,086 cervical squamous cancer cases detected by mass screening. 1) The cancer detection rate (CDR) for the 2-year successively screened group who were class I in the first screening was 0.051% and all cases were carcinoma in situ (CIS). In the 2-year interval screened group, detection rates for CIS, microinvasive cancer and stage 1b cancer were 0.053%, 0.035% and 0.018%. But there is no significant difference in CDR between the 2-year successively screened group and 2-year interval screened group (p less than 0.05). 2) In the 2-year successively screened group who were class II in the first screening, the CIS and microinvasive cancer detection rates were 0.044% and 0.022%. There is no significant difference in CDR between class I group and class II group. In the group who were class I in the first screening, we detected most cases in the stage 0 and a few cases in the stage Ia and Ib by mass screening at 2-year intervals. If the detection of a few cases in stage Ib is permitted, we can enforce mass screening for cervical squamous cancer at 2-year interval and it is considered that class II group can be screened at same interval as class I group.

摘要

为了研究宫颈癌筛查的合适间隔时间,我们主要调查了通过大规模筛查发现的1086例宫颈鳞状癌病例的筛查史。1)首次筛查为I级的连续2年筛查组的癌症检出率(CDR)为0.051%,所有病例均为原位癌(CIS)。在2年间隔筛查组中,CIS、微浸润癌和1b期癌的检出率分别为0.053%、0.035%和0.018%。但连续2年筛查组和2年间隔筛查组的CDR无显著差异(p<0.05)。2)首次筛查为II级的连续2年筛查组中,CIS和微浸润癌的检出率分别为0.044%和0.022%。I级组和II级组的CDR无显著差异。在首次筛查为I级的组中,通过2年间隔的大规模筛查,我们在0期检测到大多数病例,在Ia期和Ib期检测到少数病例。如果允许检测少数Ib期病例,我们可以每2年进行一次宫颈鳞状癌的大规模筛查,并且认为II级组可以与I级组以相同的间隔进行筛查。

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