Hando T, Kodama S, Obata N, Goto A, Takeuchi S, Aoki S
Nihon Sanka Fujinka Gakkai Zasshi. 1981 Aug;33(8):1205-8.
A total of 73,897 cases of women above 30 years old were screened for their cervical cancer by Pap smear in Niigata prefecture in 1978 and 1979. From them 37 cases of invasive cancer (0.05%) including a case of endometrial adenocarcinoma, stage II, 30 cases of carcinoma in situ (0.04%), and 52 cases of dysplasia (0.07%) were detected. From the correlation between the check up frequency of these patients and the cervical malignancy detected, the following were pointed out: 1) No invasive cancer but carcinoma in situ were detected from those patients who were cytoscreened by successive annual visits. 2) Stage Ia but not more advanced cervical cancer were detected from those patients who were screened at 2 years interval. 3) Stage Ib or farther advanced cervical cancer were detected from those patients who visited at 3 years or more years interval just like from those patients who visited for the first time. To detect cervical cancer in its preinvasive stage, annual Pap smear of adult women over 30 years old should be continued.
1978年和1979年，新潟县对73897名30岁以上的女性进行了巴氏涂片宫颈癌筛查。从中检测出37例浸润癌（0.05%），包括1例子宫内膜腺癌（II期）、30例原位癌（0.04%）和52例发育异常（0.07%）。从这些患者的检查频率与检测到的宫颈恶性肿瘤之间的相关性来看，得出以下几点：1）通过连续年度检查进行细胞筛查的患者中未检测到浸润癌，但检测到了原位癌。2）每隔2年进行筛查的患者中检测到Ia期而非更晚期的宫颈癌。3）间隔3年或更长时间就诊的患者中检测到Ib期或更晚期的宫颈癌，就像首次就诊的患者一样。为了在宫颈癌的浸润前期检测到它，30岁以上成年女性应继续每年进行巴氏涂片检查。
