病例对照研究的简化精确分析：匹配对；二分暴露
Simplified exact analysis of case-referent studies: matched pairs; dichotomous exposure.
作者信息
Liddell F D
出版信息
J Epidemiol Community Health. 1983 Mar;37(1):82-4. doi: 10.1136/jech.37.1.82.
Abstract
In a case-referent study of matched pairs with a single dichotomous exposure variable, the relative risk R is estimated from the "discordant pairs," r and s, by R = r/s. In this paper the exact (1 - alpha) confidence limits, RL and RU, have been simplified, and a new exact test of the null hypothesis that R = 1 has been derived. The exact methods depend on the F distribution; they are simple to calculate and all have been fully validated. Even after simplification, methods for obtaining approximations to RL and RU remain more unwieldy than the exact methods, and an evaluation shows that these approximations may occasionally be far from the truth. It is argued that there is no excuse for not using the exact methods.
摘要
在一项针对具有单个二分暴露变量的匹配对的病例对照研究中，相对风险R通过“不一致对”r和s估计，即R = r/s。本文简化了确切的（1 - α）置信限RL和RU，并推导了关于R = 1的原假设的新的确切检验方法。确切方法依赖于F分布；它们计算简单且均已得到充分验证。即使经过简化，获得RL和RU近似值的方法仍比确切方法更繁琐，并且一项评估表明这些近似值偶尔可能与实际情况相差甚远。有人认为没有理由不使用确切方法。
相似文献
1
Simplified exact analysis of case-referent studies: matched pairs; dichotomous exposure.病例对照研究的简化精确分析：匹配对；二分暴露
J Epidemiol Community Health. 1983 Mar;37(1):82-4. doi: 10.1136/jech.37.1.82.
2
Matched case-control designs and overmatched analyses.匹配病例对照设计和过度匹配分析。
Am J Epidemiol. 1986 Oct;124(4):693-701. doi: 10.1093/oxfordjournals.aje.a114443.
3
Exact unconditional tests for testing non-inferiority in matched-pairs design.用于配对设计中非劣效性检验的精确无条件检验。
Stat Med. 2003 Jan 30;22(2):265-78. doi: 10.1002/sim.1261.
4
Exact versus asymptotic analysis for a matched case-control study.匹配病例对照研究的精确分析与渐近分析
Stat Med. 1988 Jul;7(7):765-72. doi: 10.1002/sim.4780070706.
5
Simple exact analysis of the standardised mortality ratio.标准化死亡率比的简单精确分析。
J Epidemiol Community Health. 1984 Mar;38(1):85-8. doi: 10.1136/jech.38.1.85.
6
A simplification and implementation of random-effects meta-analyses based on the exact distribution of Cochran's Q.基于 Cochr an's Q 精确分布的随机效应荟萃分析的简化与实现
Methods Inf Med. 2014;53(1):54-61. doi: 10.3414/ME13-01-0073. Epub 2013 Dec 9.
7
Estimating confidence limits on a standardised mortality ratio when the expected number is not error free.当预期死亡数并非无误差时，估计标准化死亡比的置信区间。
J Epidemiol Community Health. 1994 Jun;48(3):313-7. doi: 10.1136/jech.48.3.313.
8
Power calculation in matched case-referent studies. Application and accuracy of the asymptotic power function.配对病例对照研究中的功效计算。渐近功效函数的应用与准确性。
Am J Epidemiol. 1986 Nov;124(5):836-42. doi: 10.1093/oxfordjournals.aje.a114460.
9
Overadjustment in case-control studies.病例对照研究中的过度调整。
Am J Epidemiol. 1980 Nov;112(5):696-706. doi: 10.1093/oxfordjournals.aje.a113042.
10
Estimability and estimation in case-referent studies.病例对照研究中的可估计性与估计
Am J Epidemiol. 1976 Feb;103(2):226-35. doi: 10.1093/oxfordjournals.aje.a112220.
引用本文的文献
1
Insights on Telecommunication Use by Rehabilitation Therapists Before, During, and Beyond COVID-19.康复治疗师在新冠疫情之前、期间及之后使用电信技术的见解
Arch Rehabil Res Clin Transl. 2024 Feb 13;6(2):100326. doi: 10.1016/j.arrct.2024.100326. eCollection 2024 Jun.
2
Comparative efficacy of two different topical povidone-iodine 5% regimens in reducing conjunctival bacterial flora: A randomized parallel double-masked clinical trial.两种不同的5%聚维酮碘局部用药方案在减少结膜细菌菌群方面的疗效比较：一项随机平行双盲临床试验。
PLoS One. 2017 Dec 19;12(12):e0189206. doi: 10.1371/journal.pone.0189206. eCollection 2017.
3
Cancer-related fatigue: appraising evidence-based guidelines for screening, assessment and management.癌症相关疲劳：评估筛查、评估及管理的循证指南
Support Care Cancer. 2016 Sep;24(9):3935-42. doi: 10.1007/s00520-016-3228-9. Epub 2016 Apr 26.
4
What Do You Think Would Make You Happier? What Do You Think You Would Choose?().你认为什么会让你更快乐？你认为你会选择什么？（）
Am Econ Rev. 2012 Aug;102(5):2083-2110. doi: 10.1257/aer.102.5.2083.
5
Obesity-related metabolic dysfunction in dogs: a comparison with human metabolic syndrome.犬肥胖相关代谢功能障碍：与人类代谢综合征的比较。
BMC Vet Res. 2012 Aug 28;8:147. doi: 10.1186/1746-6148-8-147.
6
Interacting effects of vision and attention in perceiving spontaneous sensations arising on the hands.手自发感觉知觉中的视觉和注意的交互作用。
Exp Brain Res. 2012 Jan;216(1):21-34. doi: 10.1007/s00221-011-2901-y. Epub 2011 Oct 19.
7
The long-term outcome after severe trauma of children in Flanders (Belgium): a population-based cohort study using the International Classification of Functioning--related outcome score.儿童在佛兰德斯（比利时）遭受严重创伤后的长期预后：一项基于人群的队列研究，使用国际功能、残疾和健康分类相关结果评分。
Eur J Pediatr. 2011 Jan;170(1):65-73. doi: 10.1007/s00431-010-1271-y. Epub 2010 Aug 10.
8
Irreversible JPEG 2000 compression of abdominal CT for primary interpretation: assessment of visually lossless threshold.用于初步解读的腹部CT的不可逆JPEG 2000压缩：视觉无损阈值评估
Eur Radiol. 2007 Jun;17(6):1529-34. doi: 10.1007/s00330-006-0509-6. Epub 2006 Nov 22.
9
NS1 protein secretion during the acute phase of West Nile virus infection.西尼罗河病毒感染急性期的NS1蛋白分泌
J Virol. 2005 Nov;79(22):13924-33. doi: 10.1128/JVI.79.22.13924-13933.2005.
本文引用的文献
1
Statistical aspects of the analysis of data from retrospective studies of disease.疾病回顾性研究数据的统计分析方面
J Natl Cancer Inst. 1959 Apr;22(4):719-48.
Zotero 插件