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视网膜母细胞瘤中4-羟基-3-甲氧基扁桃酸(HMMA)的排泄情况

4-hydroxy-3-methoxymandelic acid (HMMA) excretion in retinoblastoma.

作者信息

Dias P L, Amarasiri A A

出版信息

Br J Ophthalmol. 1978 Aug;62(8):525-7. doi: 10.1136/bjo.62.8.525.

Abstract

4-Hydroxy-3-methoxymandelic acid (HMMA) concentrations in aqueous humour, urine, and serum were simultaneously estimated to determine if these levels were raised in cases of retinoblastoma. The catecholamine content of aqueous humour was significantly higher than that of urine and serum, but as there was no significant difference in the HMMA concentration in retinoblastoma and other non-malignant conditions it seems likely that retinoblastoma is not a catecholamine-secreting tumour.

摘要

同时测定房水、尿液和血清中4-羟基-3-甲氧基扁桃酸(HMMA)的浓度,以确定视网膜母细胞瘤患者的这些水平是否升高。房水中儿茶酚胺含量显著高于尿液和血清,但由于视网膜母细胞瘤与其他非恶性疾病的HMMA浓度无显著差异,因此视网膜母细胞瘤似乎不是一种分泌儿茶酚胺的肿瘤。

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本文引用的文献

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Urinary vanilmandelic acid (VMA) excretion in children: use of a simple semiquantitative test.
J Pediatr. 1963 Jun;62:844-54. doi: 10.1016/s0022-3476(63)80098-0.

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