外科随机前瞻性试验的实践与伦理缺陷
The practical and ethical defects of surgical randomised prospective trials.
作者信息
Byer A
出版信息
J Med Ethics. 1983 Jun;9(2):90-3. doi: 10.1136/jme.9.2.90.
Abstract
This paper presents a strong criticism of the current enthusiasm for clinical randomised prospective studies in surgery. In the process, the author probes the 'intellectualism' or lack thereof in present day surgical attitudes. The subjects are examined against a framework of ethics and inescapable dilemmas. Ways of correcting the more obvious weaknesses are suggested. The manuscript is, and is meant to be, provocative and is particularly aimed at the academic audience served by this journal.
摘要
本文对当前外科临床随机前瞻性研究的热潮提出了强烈批评。在此过程中，作者探究了当今外科态度中存在或缺乏的“唯理智论”。依据伦理框架和不可避免的困境对这些问题进行了审视，并提出了纠正较为明显弱点的方法。该手稿具有，且旨在具有煽动性，尤其针对本期刊所服务的学术读者群体。
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本文引用的文献
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Scientific empiricism and clinical medicine: a discussion paper.科学经验主义与临床医学：一篇讨论文章。
J R Soc Med. 1981 Jul;74(7):504-9. doi: 10.1177/014107688107400710.
2
Controlled clinical trials: the current ethical debate.对照临床试验：当前的伦理辩论。
J R Soc Med. 1981 Feb;74(2):85-8. doi: 10.1177/014107688107400201.
3
Randomized versus historical controls for clinical trials.临床试验中的随机对照与历史对照
Am J Med. 1982 Feb;72(2):233-40. doi: 10.1016/0002-9343(82)90815-4.
4
The propagation of Lister's ideas.李斯特思想的传播。
Surg Gynecol Obstet. 1968 Nov;127(5):1081-6.
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