Maatman T J, Novick A C, Montague D K, Levin H S
J Urol. 1983 Aug;130(2):338-9. doi: 10.1016/s0022-5347(17)51138-6.
Intracavitary irradiation is effective in the treatment of noninvasive papillary transitional cell carcinoma and carcinoma in situ of the bladder. Mortality has not been associated with this form of therapy. The morbidity associated with intracavitary irradiation consists of mild to severe radiation cystitis and we report 2 such cases. One patient is from a series of 65 patients with noninvasive bladder tumors treated with intracavitary irradiation at this clinic since 1965. The second patient had noninvasive bladder tumors and was treated with intracavitary irradiation elsewhere. In both patients severe radiation cystitis subsequently developed, requiring simple cystectomy and urinary diversion. The potential for this serious side effect must be considered when choosing a form of therapy for patients with noninvasive papillary transitional cell carcinoma and carcinoma in situ of the bladder.
腔内照射对治疗非侵袭性乳头状移行细胞癌和膀胱原位癌有效。这种治疗方式未导致死亡。腔内照射相关的发病率包括轻度至重度放射性膀胱炎,我们报告2例此类病例。1例患者来自自1965年起在本诊所接受腔内照射治疗的65例非侵袭性膀胱肿瘤患者系列。第2例患者有非侵袭性膀胱肿瘤,在其他地方接受了腔内照射治疗。两名患者随后均发生了严重放射性膀胱炎,需要进行单纯膀胱切除术和尿流改道。在为非侵袭性乳头状移行细胞癌和膀胱原位癌患者选择治疗方式时,必须考虑到这种严重副作用的可能性。