Kasai N, Sakamoto A
Gan No Rinsho. 1983 Feb;29(2):A-7, 105-10.
The prognosis of thyroid cancer depends largely on histological differentiation and clinical stage. The prognosis in anaplastic cancer is worst, in well differentiated cancer it is best; poorly differentiated cancer takes a middle position. The prognosis of patients with differentiated cancer is generally good, however, there are cases with malignant transformation such as poorly differentiated, anaplastic and squamous-cell cancer transformation. We studied the frequency and the inducement factors of malignant transformation in patients with thyroid cancer. The frequency of poorly differentiated, anaplastic and squamous-cell cancer transformation was 13.6%, 6.4% and 0.7%, respectively. In anaplastic cancer transformation, irradiation is an important factor.
甲状腺癌的预后很大程度上取决于组织学分化和临床分期。未分化癌的预后最差，高分化癌的预后最好；低分化癌则处于中间位置。分化型癌患者的预后总体良好，然而，也存在恶性转化的病例，如向低分化、未分化和鳞状细胞癌转化。我们研究了甲状腺癌患者恶性转化的频率及诱发因素。低分化、未分化和鳞状细胞癌转化的频率分别为13.6%、6.4%和0.7%。在未分化癌转化中，辐射是一个重要因素。
