Shanmugasundaram K R, Seethapathy P G, Shanmugasundaram E R
J Ethnopharmacol. 1983 May;7(3):247-65. doi: 10.1016/0378-8741(83)90001-6.
The procedure for the preparation of Anna Pavala Sindhooram (APS), a drug based on the concepts of Indian medicine for the prevention and reversal of the atherosclerotic disease process is described in detail. The uniformity in the composition of samples of the drug obtained in 10 batches, prepared over a period of 5 years is evident from the chemical analysis of the mineral constituents. The possibility of iodine, copper, iron, calcium and magnesium present in the Anna Pavala Sindhooram, acting metabolically to reduce hypercholesterolemia is discussed. The ingredients used are green vitriol (Annabedi or ferrous sulphate), coral reef (Corallium rubrum or Pavalam), leaves of Acalypha indica (Kuppaimeni), Lippia nodiflora (Poduthalai), Vinca rosea (Nityakalyani), Lawsonia alba (maruthondri) and Cynodon dactylon (Arugampul) and the flowers of Hibiscus rosasinensis (Chemparathampoo) and the ripe fruits of Phyllanthus emblica (nellikkai). Sindhooram is the chief therapeutic form of herbo-mineral preparations used in the Sidha system of Indian medicine.
详细介绍了一种基于印度医学理念、用于预防和逆转动脉粥样硬化疾病进程的药物——安娜·帕瓦拉·辛杜拉姆（APS）的制备过程。从对矿物质成分的化学分析可以明显看出，在5年时间内制备的10批该药物样品成分的均匀性。文中讨论了安娜·帕瓦拉·辛杜拉姆中所含的碘、铜、铁、钙和镁通过代谢作用降低高胆固醇血症的可能性。所使用的成分有绿矾（安纳贝迪或硫酸亚铁）、珊瑚礁（红珊瑚或帕瓦拉姆）、印度铁苋菜（库帕伊梅尼）的叶子、垂序马缨丹（波杜萨莱）、长春花（尼提亚卡利亚尼）、白番泻叶（马鲁通德里）、狗牙根（阿鲁甘普尔）、朱槿（钦帕拉通普）的花以及余甘子（内利凯）的成熟果实。辛杜拉姆是印度医学悉达体系中使用的草药 - 矿物质制剂的主要治疗形式。
