Kaneda Y, Bello-Reuss E
Miner Electrolyte Metab. 1983;9(3):147-50.
The effect of dopamine (10(-6) M) on PO4 reabsorption was studied in isolated and perfused proximal convoluted and straight tubules of the rabbit. In convoluted tubules, fluid reabsorption (JV), PO4 lumen-to-bath (JPO4lb), and net (net JPO4) fluxes did not change during dopamine exposure. In S3 segments bathed in rabbit serum, JV diminished significantly during dopamine exposure. JPO4 decreased by 20% (p less than 0.005) and net JPO4 decreased by 27% (p less than 0.02). The effect of dopamine was reversible upon removal of the drug.
在兔离体灌注的近端曲管和直管中研究了多巴胺（10⁻⁶ M）对磷酸根（PO₄）重吸收的影响。在曲管中，多巴胺作用期间液体重吸收（JV）、PO₄从管腔到浴液的通量（JPO₄lb）和净通量（净JPO₄）均未改变。在浸浴于兔血清中的S3节段，多巴胺作用期间JV显著降低。JPO₄降低了20%（p<0.005），净JPO₄降低了27%（p<0.02）。去除药物后，多巴胺的作用是可逆的。
