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[儿童各种疾病中尾状核神经细胞内的酒精性透明样小体]

[Alcoholic hyaline-like bodies in nerve cells of the caudate nuclei in various diseases of children].

作者信息

Ogawa H, Ikuta F, Oyake Y

出版信息

No To Shinkei. 1977 Feb;29(2):215-8.

PMID:68781
Abstract

Intracytoplasmic hyaline bodies were noticed in nerve cells of the caudate nuclei of the infantile diseases: Leigh's encephalomyelopathy (12-year-old, male), Wilson's disease (14-year-old, male), Morquio's disease (12-year-old, male), pseudoulegyric type of hepatocerebral degeneration (19-year-old, male) and Schilder's disease (15-year-old, male). The hyeline bodies were noticed as linear, striate, dendritic or antler-like in form and stained pink or red with hematoxylin-eosin, orange or red with tmasson trichrome, and dark blue or purple with phosphotungstic acid hematoxylin. The characteristics of the neuronal inclusions have much resemblance to the "alcoholic hyaline-like bodies" which were described by K. Kojima in the caudate nuclei of alcoholics. The results may indicate that the presence of the hyaline bodies in the caudate nucleus is not pathognomonic for alcoholic intoxication, but may suggest the presence of a certain common metabolic disorder among the described diseases.

摘要

在以下婴儿疾病的尾状核神经细胞中发现了胞质内透明小体

Leigh 脑脊髓病(12岁,男性)、威尔逊病(14岁,男性)、莫尔基奥氏病(12岁,男性)、假癫痫型肝脑变性(19岁,男性)和席尔德病(15岁,男性)。透明小体呈线性、条纹状、树枝状或鹿角状,苏木精-伊红染色呈粉红色或红色,马森三色染色呈橙色或红色,磷钨酸苏木精染色呈深蓝色或紫色。神经元包涵体的特征与小岛健二在酒精中毒者尾状核中描述的“酒精性透明样小体”非常相似。结果可能表明,尾状核中透明小体的存在并非酒精中毒的特征性表现,但可能提示在所描述的疾病中存在某种共同的代谢紊乱。

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