Alcoholic hyalin-like bodies found in the pancreatic acinar cells and nerve cells of the brain.

The presence of hyalinoid body as an eosinophilic, dendriform to irregularly shaped mass was noted in the cytoplasm of pancreatic acinar cells of 13 among a series of approximately 150 autopsy cases of alcoholism examined. Similar subcellular structures were also demonstrable in nerve cells of the brain in 2 of these cases. The hyalinoid body stained scarlet in phloxine methylene blue preparations and orange-brown in preparations with the Masson staining method (modified procedure of Gomori), and was revealed to be a fibrillar filamentous mass by electron microscopy. These characteristics suggest its marked resemblance to alcoholic hyalin in liver cells.