An integrated programme of haemodialysis and peritoneal dialysis: a single two-litre exchange per night plus haemodialysis every four to six days.

Critical problems of CAPD: (a) protein loss; (b) peritonitis; (c) glucose overload; (d) intra-abdominal pressure, can be rationally managed by an integrated intracorporeal and extracorporeal approach. A single two-litre peritoneal exchange performed during the night in addition to haemodialysis every four to six days (HD-PD) reduces a, b, c and eliminates d. This HD-PD technique has been evaluated in eight uraemic patients over a total period of 20.5 patient months. Preliminary results show that this procedure can provide adequate biochemical control, with low protein losses and limited interdialysis weight gain.