Spector A C, Smith J C, Hollander G R
Physiol Behav. 1983 Apr;30(4):647-9. doi: 10.1016/0031-9384(83)90236-6.
Seventy-two hours after saccharin (CS) was paired with either a 100R or sham radiation exposure, rats received a 0-, 3-, 6-, 12-, 24-, or 46-hour saccharin-alone presentation followed by a 23-hour two-bottle preference test. Generally, faster recovery from the aversion was observed in animals receiving longer CS-alone presentations. The present procedure differs from previous work done with other toxins in that animals were not fluid-deprived during the postconditioning period. This enabled animals to constantly control the volume, duration, and inter-bout interval of the saccharin drinking episodes independent of any experimentally imposed drinking schedule. In addition, the two-bottle test provided a sensitive measure of the status of the saccharin aversion following the saccharin-alone presentation.
在糖精（条件刺激物）与100伦琴辐射暴露或假辐射暴露配对72小时后，大鼠接受0小时、3小时、6小时、12小时、24小时或46小时单独给予糖精的实验，随后进行23小时的双瓶偏好测试。一般来说，在接受单独给予糖精时间更长的动物中，观察到厌恶反应的恢复更快。本实验程序与先前使用其他毒素所做的工作不同，在于在条件作用后的时期动物没有被剥夺液体。这使得动物能够独立于任何实验设定的饮水时间表，持续控制糖精饮用时段的量、持续时间和两次饮用之间的间隔。此外，双瓶测试提供了一种在单独给予糖精后对糖精厌恶状态的敏感测量方法。
