Gronan R J, Schadt J C, York D H
Physiol Behav. 1983 May;30(5):719-22. doi: 10.1016/0031-9384(83)90168-3.
A method for preparation and application of an indwelling catheter for measurement of aortic pressure in conscious rabbits is described. The catheter is generally reliable for periods longer than one month and requires little interference with the normal circulation. The system utilizes coiled polyethylene tubing which has a tapered tip covered with silicone rubber tubing and, at its exterior end, a Velcro matrix for skin healing. The catheter tip is pulled into the abdominal aorta with a trocar, directed caudally. The exterior end is run subcutaneously to the nape of the neck. In 19 rabbits prepared by this method, mean pressure was determined to be 68 +/- 2 mm Hg and pulse pressure was 29 +/- 1 mm Hg two weeks after implantation. The catheters remained patent in 17 rabbits at the time of sacrifice, 12 to 120 days later. In an in vitro sweep-frequency test, maximal resonance of the catheter system was found to lie between 12-14 Hz, at which point the measured pressure amplitude exceeded control by 12.5%.
描述了一种用于清醒兔主动脉压力测量的留置导管的制备和应用方法。该导管在超过一个月的时间内通常可靠，并且对正常循环的干扰很小。该系统使用盘绕的聚乙烯管，其具有覆盖有硅橡胶管的锥形尖端，并且在其外端具有用于皮肤愈合的尼龙搭扣矩阵。用套管针将导管尖端拉入股主动脉，并指向尾侧。外端经皮下延伸至颈部后方。用这种方法制备的19只兔中，植入两周后平均压力测定为68±2 mmHg，脉压为29±1 mmHg。在处死时（12至120天后），17只兔的导管保持通畅。在体外扫频测试中，发现导管系统的最大共振频率在12 - 14 Hz之间，此时测量的压力幅度比对照超出12.5%。
