Dimitrov D, Girchev R
Acta Physiol Acad Sci Hung. 1981;57(2):185-9.
A modification of the method of BROOKS and MUIRHEAD [2] for long-term measurement of aortic pressure in rabbits is presented. The original abdominal surgical approach is replaced by a flank extraperitoneal incision and the construction of the catheter is simplified and adapted to the new surgical procedure. The preparation and implantation of the catheter as well as the pressure recording technique are described. Using the modified catheter pulsatile and mean aortic pressure could be measured in conscious rabbits several months. Owing to the flank approach, surgical trauma and the risk of intra-abdominal infection could be minimized. On the other hand, this technique allowed simultaneous extraperitoneal procedures involving the aorta and kidney, permitting more complex haemodynamic studies.
本文介绍了一种对BROOKS和MUIRHEAD [2]的方法进行改良后的技术，用于长期测量兔主动脉压力。原有的腹部手术入路被侧腹腹膜外切口所取代，并且导管的构造得到简化并适应了新的手术操作。文中描述了导管的制备、植入以及压力记录技术。使用改良后的导管，可以在清醒兔身上测量数月的搏动性和平均主动脉压力。由于采用了侧腹入路，手术创伤和腹腔内感染风险得以降至最低。另一方面，该技术允许同时进行涉及主动脉和肾脏的腹膜外操作，从而能够开展更复杂的血流动力学研究。
