• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

能量代谢的3/4质量指数并非统计假象。

The 3/4 mass exponent for energy metabolism is not a statistical artifact.

作者信息

Feldman H A, McMahon T A

出版信息

Respir Physiol. 1983 May;52(2):149-63. doi: 10.1016/0034-5687(83)90002-6.

DOI:10.1016/0034-5687(83)90002-6
PMID:6878906
Abstract

The scaling law eta = alpha Mb is used to model basal energy metabolism (eta) in terms of body mass (M). The exponent b = 3/4 has commonly been applied to either inter-specific or intra-specific variation of body mass (the 'Brody-Kleiber law'). Heusner recently demonstrated that the exponent 2/3 provided a better description of intra-specific variation in a set of animal data from the literature and dismissed the value 3/4 as a 'statistical artifact.' Using the same data, we recast the statistical analysis in mathematically equivalent form and show that 3/4 nonetheless emerges as a precise numerical estimate of the mass exponent for inter-specific variation. We relate this finding to the theory of elastic similarity and demonstrate that there is both experimental and theoretical justification for the use of both exponents in describing the variation of basal energy metabolism among animals of different size and species.

摘要

标度律η = αM^b用于根据体重(M)对基础能量代谢(η)进行建模。指数b = 3/4通常应用于种间或种内体重变化(“布罗迪-克莱伯定律”)。休斯纳最近证明,指数2/3能更好地描述文献中一组动物数据的种内变化,并摒弃了3/4这个值,认为它是“统计假象”。我们使用相同的数据,以数学等价形式重新进行统计分析,结果表明,对于种间变化,3/4仍然是质量指数的精确数值估计。我们将这一发现与弹性相似性理论联系起来,并证明在描述不同大小和物种的动物基础能量代谢变化时,使用这两个指数都有实验和理论依据。

相似文献

1
The 3/4 mass exponent for energy metabolism is not a statistical artifact.能量代谢的3/4质量指数并非统计假象。
Respir Physiol. 1983 May;52(2):149-63. doi: 10.1016/0034-5687(83)90002-6.
2
Size matters in metabolic scaling: Critical role of the thermodynamic efficiency of ATP synthesis and its dependence on mitochondrial H leak across mammalian species.在代谢比例关系中,大小很重要:三磷酸腺苷合成的热力学效率及其对哺乳动物物种中线粒体 H 渗漏的依赖性起着关键作用。
Biosystems. 2024 Aug;242:105255. doi: 10.1016/j.biosystems.2024.105255. Epub 2024 Jun 19.
3
Body size, energy metabolism and lifespan.体型、能量代谢与寿命。
J Exp Biol. 2005 May;208(Pt 9):1717-30. doi: 10.1242/jeb.01556.
4
Energy metabolism and body size. I. Is the 0.75 mass exponent of Kleiber's equation a statistical artifact?能量代谢与体型。I. 克莱伯方程中0.75的质量指数是统计假象吗?
Respir Physiol. 1982 Apr;48(1):1-12. doi: 10.1016/0034-5687(82)90046-9.
5
Allometric scaling of mammalian metabolism.哺乳动物新陈代谢的异速生长缩放
J Exp Biol. 2005 May;208(Pt 9):1611-9. doi: 10.1242/jeb.01501.
6
Beyond the '3/4-power law': variation in the intra- and interspecific scaling of metabolic rate in animals.超越“3/4 幂定律”:动物种内和种间代谢率缩放的变化
Biol Rev Camb Philos Soc. 2005 Nov;80(4):611-62. doi: 10.1017/S1464793105006834.
7
Scaling of basal metabolic rate with body mass and temperature in mammals.哺乳动物基础代谢率与体重和温度的关系。
J Anim Ecol. 2010 May;79(3):610-9. doi: 10.1111/j.1365-2656.2010.01672.x. Epub 2010 Feb 18.
8
Dimensional analysis does not determine a mass exponent for metabolic scaling.
Am J Physiol. 1987 Jul;253(1 Pt 2):R195-9. doi: 10.1152/ajpregu.1987.253.1.R195.
9
On the thermodynamic origin of metabolic scaling.代谢缩放的热力学起源。
Sci Rep. 2018 Jan 23;8(1):1448. doi: 10.1038/s41598-018-19853-6.
10
The origin of allometric scaling laws in biology.生物学中异速生长比例定律的起源。
J Theor Biol. 2006 Dec 21;243(4):455-67. doi: 10.1016/j.jtbi.2006.05.031. Epub 2006 Jun 7.

引用本文的文献

1
Impact of developmental temperature on neural growth, connectivity, and function.发育温度对神经生长、连接性及功能的影响。
Sci Adv. 2025 Jan 17;11(3):eadp9587. doi: 10.1126/sciadv.adp9587. Epub 2025 Jan 15.
2
Bacterial sepsis triggers stronger transcriptomic immune responses in larger primates.细菌败血症在较大的灵长类动物中引发更强的转录组免疫反应。
Proc Biol Sci. 2024 Jun;291(2025):20240535. doi: 10.1098/rspb.2024.0535. Epub 2024 Jun 26.
3
Metabolic Rates of Japanese Anchovy () during Early Development Using a Novel Modified Respirometry Method.
采用新型改良呼吸测量法研究日本鳀早期发育阶段的代谢率
Animals (Basel). 2023 Mar 12;13(6):1035. doi: 10.3390/ani13061035.
4
Metabolic scaling: individual versus intraspecific scaling of Nile tilapia (Oreochromis niloticus).代谢率个体与种内尺度变化:尼罗罗非鱼(Oreochromis niloticus)。
J Comp Physiol B. 2021 Jul;191(4):721-729. doi: 10.1007/s00360-021-01376-8. Epub 2021 May 2.
5
Research tools for extrapolating the disposition and pharmacokinetics of nanomaterials from preclinical animals to humans.从临床前动物外推纳米材料的处置和药代动力学的研究工具。
Theranostics. 2019 May 18;9(11):3365-3387. doi: 10.7150/thno.34509. eCollection 2019.
6
On the thermodynamic origin of metabolic scaling.代谢缩放的热力学起源。
Sci Rep. 2018 Jan 23;8(1):1448. doi: 10.1038/s41598-018-19853-6.
7
Comparative metabolic ecology of tropical herbivorous echinoids on a coral reef.珊瑚礁上热带草食性海胆的比较代谢生态学
PLoS One. 2018 Jan 18;13(1):e0190470. doi: 10.1371/journal.pone.0190470. eCollection 2018.
8
Allometry and Scaling of the Intraocular Pressure and Aqueous Humour Flow Rate in Vertebrate Eyes.脊椎动物眼睛眼压与房水流量的异速生长和比例关系
PLoS One. 2016 Mar 18;11(3):e0151490. doi: 10.1371/journal.pone.0151490. eCollection 2016.
9
Ontogenetic phase shifts in metabolism in a flounder Paralichthys olivaceus.牙鲆(Paralichthys olivaceus)新陈代谢的个体发生阶段变化
Sci Rep. 2014 Nov 20;4:7135. doi: 10.1038/srep07135.
10
Dosing in children: a critical review of the pharmacokinetic allometric scaling and modelling approaches in paediatric drug development and clinical settings.儿童用药剂量:儿科药物研发和临床环境中药代动力学异速生长比例缩放及建模方法的批判性综述
Clin Pharmacokinet. 2014 Apr;53(4):327-46. doi: 10.1007/s40262-014-0134-5.