Doury P, Pattin S, Eulry F, Maurel C, Masson C, Tabaraud F
Rev Rhum Mal Osteoartic. 1983 Apr;50(4):277-80.
The authors report two cases of Horton's disease and one case of rhizomelic pseudopolyarthritis treated initially with delta-cortisone with a very rapid favourable result. However, while under relatively high dose steroid therapy, there was recurrence of the disease in the three cases and the development of complications of steroid therapy prohibited the use of higher doses of delta-cortisone and even required its rapid weaning. In these three cases, the addition of 100 mg of dapsone per day led to a rapid control of the disease, with return to normal of the erythrocyte sedimentation rate and reduction of the doses of delta-cortisone. The authors discuss the place of dapsone in the treatment of Horton's disease and rhizomelic pseudopolyarthritis in the light of these three cases.
作者报告了两例霍顿病和一例肢根性假多关节炎病例，最初用δ-可的松治疗，取得了非常迅速的良好效果。然而，在相对高剂量的类固醇治疗期间，这三例病例均出现了疾病复发，且类固醇治疗的并发症发展使得无法使用更高剂量的δ-可的松，甚至需要迅速撤药。在这三例病例中，每天加用100毫克氨苯砜可迅速控制疾病，红细胞沉降率恢复正常，δ-可的松剂量减少。作者根据这三例病例讨论了氨苯砜在霍顿病和肢根性假多关节炎治疗中的地位。
