Sherenesheva N I
Vopr Onkol. 1983;29(7):80-4.
Rats reveal distinct variations in response to carcinogenic action. The highest frequency of stomach tumors (69.6%) and the shortest period of their development (54.7 weeks) were registered in noninbred rats. Multiple lesions of the gastrointestinal tract were relatively frequent, too. Augustus and Penguin rats responded with a high frequency of tumor development. However, tumors arose in them later than in noninbred rats. Wistar rats appeared to be relatively resistant to MNNG action.
大鼠对致癌作用的反应存在明显差异。非近交系大鼠的胃肿瘤发生率最高（69.6%），其发生时间最短（54.7周）。胃肠道的多处病变也相对常见。奥古斯塔斯大鼠和企鹅大鼠的肿瘤发生率较高。然而，它们的肿瘤发生时间比非近交系大鼠晚。Wistar大鼠似乎对MNNG作用相对耐药。
