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[Induction of gastrointestinal tract tumors in rats with N-methyl-N-nitro-N-nitrosoguanidine (MNNG)].

作者信息

Sherenesheva N I

出版信息

Vopr Onkol. 1979;25(8):72-4.

PMID:483704
Abstract

Tumors of the gastrointestinal tract were induced in white non-inbred rats exposed to MNNG in various doses. Gastric tumors appeared in the dosage of 153 mg, with its 2 and 3.3 times increase no change in the frequency of gastric tumors was noted. The frequency of jejunal tumors was higher with increased MNNG dosage.

摘要

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Vopr Onkol. 1979;25(8):72-4.
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Inhibitory effects of tetragastrin and histamine on carcinogenesis in the small intestines of W rats by N-methyl-N'-nitro-N-nitrosoguanidine.四肽胃泌素和组胺对N-甲基-N'-硝基-N-亚硝基胍诱导的W大鼠小肠癌变的抑制作用。
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