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用于检测抗髓磷脂致脑炎蛋白抗体的免疫化学方法比较

A comparison of immunochemical methods for the detection of antibodies to myelin encephalitogenic protein.

作者信息

Whitaker J N, McFarlin D E

出版信息

Brain Res. 1977 Jun 24;129(1):121-8. doi: 10.1016/0006-8993(77)90974-x.

Abstract

The antibody titer to myelin encephalitogenic protein in rabbits and rats has been comparatively studied by double antibody radioimmunoassay, quantitative microcomplement fixation, and radioimmunoelectrophoresis. In general, these immunochemical tests quantitatively paralleled one another but minor differences were sometimes present. The desirability of using a combination of these methods in assesing the antibody response to myelin encephalitogenic protein is emphasized.

摘要

已通过双抗体放射免疫测定、定量微量补体结合试验和放射免疫电泳对兔和大鼠体内针对髓鞘致脑炎蛋白的抗体滴度进行了比较研究。总体而言,这些免疫化学检测在定量方面相互平行,但有时也存在细微差异。强调了在评估针对髓鞘致脑炎蛋白的抗体反应时联合使用这些方法的必要性。

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