Suppr超能文献

[尸检结果中疾病的巧合与生物学关联]

[Coincidence and biological association of diseases in autopsy findings].

作者信息

Künnert B

出版信息

Zentralbl Allg Pathol. 1983;127(5-6):343-5.

PMID:6880443
Abstract

It is known that in autopsies severe arteriosclerosis and myocardial infarction are less frequently associated with liver cirrhoses and carcinomas (except bronchial carcinoma) than with other cases. This does not mean that liver cirrhosis and carcinoma protect from vascular diseases, but the higher mortality rate if liver cirrhoses, carcinomas, and vascular diseases plays an essential role and most be taken into consideration, when conclusions concerning biological connections shall be drawn from autopsy-statistical examinations. In a certain age group, e.g. in males aged 50, in the autopsy material severe arterioscleroses are more frequent than in the living population of the same age, since the death rate (number of deceased patients as related to the total number of patients) is high for cases with circulatory diseases and vascular diseases, respectively. Liver cirrhoses, carcinomas (also with high death rates), and other diseases causing death come from the total living population with healthier (less changed) vessels and, therefore, of course they must be less frequently combined with severe arteriosclerosis and myocardial infarction than the total number of death cases, for which the distribution of arteriosclerosis in all death cases is essentially determined by the number of patients who died from the sequelae of a vascular disease. The correctness of this consideration is mathematically proved by a simple model example.

摘要

众所周知,在尸检中,与其他病例相比,严重动脉硬化和心肌梗死与肝硬化及癌症(支气管癌除外)的关联较少。这并不意味着肝硬化和癌症能预防血管疾病,而是在从尸检统计检查得出关于生物学联系的结论时,肝硬化、癌症和血管疾病较高的死亡率起着至关重要的作用,必须予以考虑。在某个年龄组,例如50岁男性中,尸检材料中严重动脉硬化比同年龄的活着人群中更为常见,因为循环系统疾病和血管疾病患者的死亡率(死亡患者数量与患者总数之比)分别很高。肝硬化、癌症(死亡率也很高)以及其他导致死亡的疾病来自血管更健康(变化较小)的总体活着人群,因此,它们当然比所有死亡病例总数更不常与严重动脉硬化和心肌梗死同时出现,因为所有死亡病例中动脉硬化的分布基本上由死于血管疾病后遗症的患者数量决定。通过一个简单的模型示例从数学上证明了这种考虑的正确性。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验