Dzugaeva S B, Biriuchkov Iu V, L'vovich A I, Semin A A
Zh Nevropatol Psikhiatr Im S S Korsakova. 1983;83(5):670-5.
Results of a pathomorphological, experimental and clinical study designed to ascertain morphological changes associated with impairment of vital visceral functions following spinal cord trauma are presented. Clinical manifestations of such disorders were studied in 127 patients with complicated vertebral fractures. Further investigations involved postmortem examination of the brain of four patients with complete anatomical rupture of the spinal cord at the level of CV, CVI, and LI segments as well as the brain of 18 mature cats with various types of spinal cord resection which were treated by silver impregnation according to Bilshovsky, Naute with the final staining of the nuclear structures according to Kawamura-Niimy. Widespread degenerative changes in the ascending conduction tracts of the spinal cord leading to the structures of the cerebral trunk were revealed. Disruptions of respiratory and cardiovascular activities secondary to complete traumatic rupture of the lower cervical segments of the spinal cord appear to be caused by impaired conduction along the ascending tracts of the spinal cord leading to the nuclei of the reticular formation of the cerebral trunk, mainly those of giant and small cells, nuclei of the vagus nerve (dorsal one and that of the solitary tract), locus coeruleus, mesencephalic nuclei of the trigeminal nerve and a number of other structures of the cerebral trunk.
本文展示了一项旨在确定脊髓损伤后与重要内脏功能损害相关的形态学变化的病理形态学、实验和临床研究结果。对127例伴有复杂椎体骨折的患者的此类疾病临床表现进行了研究。进一步的研究包括对4例在颈Ⅴ、颈Ⅵ和腰Ⅰ节段脊髓完全解剖性断裂患者的大脑进行尸检，以及对18只患有各种类型脊髓切除术的成年猫的大脑进行研究，这些猫按照比尔绍夫斯基、诺特的方法用银浸染处理，并根据川村-新见方法对核结构进行最终染色。研究发现脊髓通向脑干结构的上行传导束存在广泛的退行性变化。脊髓下颈段完全创伤性断裂继发的呼吸和心血管活动紊乱，似乎是由于通向脑干网状结构核（主要是巨细胞和小细胞核、迷走神经核（背侧核和孤束核）、蓝斑、三叉神经中脑核以及脑干其他一些结构）的脊髓上行传导束传导受损所致。
