Korkina M V, Malkov G F, Zavalishin I A, Vavilov S B, Adarcheva L S
Zh Nevropatol Psikhiatr Im S S Korsakova. 1983;83(5):732-7.
On the basis of clinical and follow up study of 106 patients with multiple sclerosis, including psychological tests and computerized tomography (34 observations), the authors specify the major types of psychic disorders related to this disease and represented in the form of the asthenic, hysteroformative, obsessive, and depressive syndromes, as well as in the form of an initial state with the clinical picture of organic dementia. Correlation of the examination data to computerized tomography findings usually reveals a direct relationship between the degree of psychic disorders and the severity of a cerebral injury. The authors point both to the necessity of controlling the psychic disturbances described and to their importance as a telltale sign in making the differential diagnosis of multiple sclerosis.
在对106例多发性硬化症患者进行临床及随访研究的基础上,包括心理测试和计算机断层扫描(34例观察),作者明确了与该疾病相关的主要精神障碍类型,这些类型表现为虚弱型、癔症样型、强迫型和抑郁综合征,以及具有器质性痴呆临床表现的初始状态。检查数据与计算机断层扫描结果的相关性通常显示精神障碍程度与脑损伤严重程度之间存在直接关系。作者指出既要控制所述精神障碍,又要重视其在多发性硬化症鉴别诊断中作为一种指征的重要性。