Murphy C R, Swift J G
Acta Anat (Basel). 1983;116(2):174-9. doi: 10.1159/000145740.
The proteolytic enzyme, pronase, was injected into the uterine lumen of rats. This treatment removed half the intramembranous particles (IMPs) from the apical plasma membrane of the uterine epithelial cells but tight junctions of these cells were unaffected. We conclude that at least some of the IMPs are proteinaceous in nature and suggest that IMPs not affected by pronase may be deeply embedded in the lipid bilayer.
将蛋白水解酶链霉蛋白酶注射到大鼠的子宫腔内。这种处理使子宫上皮细胞顶端质膜上的膜内颗粒（IMPs）减少了一半，但这些细胞的紧密连接未受影响。我们得出结论，至少一些IMPs本质上是蛋白质，并推测不受链霉蛋白酶影响的IMPs可能深深嵌入脂质双层中。
