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大鼠肾脏髓袢流量改变时的肾小管内压力振荡反应。

An oscillating intratubular pressure response to alterations in Henle loop flow in the rat kidney.

作者信息

Leyssac P P, Baumbach L

出版信息

Acta Physiol Scand. 1983 Mar;117(3):415-9. doi: 10.1111/j.1748-1716.1983.tb00015.x.

Abstract

We describe in gas anesthetized rats an oscillating intratubular pressure response, probably of vascular origin, sensitive to small physiological changes in fluid delivery to the distal tubule. The oscillation apparently indicates that an adjustment of vascular resistance is in operation, but at present it reveals neither the effector site (afferent and/or efferent arteriole) nor the effector mechanism (vasoconstriction and/or dilatation). The renin-angiotensin system seems to be involved in this phenomenon.

摘要

我们在气体麻醉的大鼠中描述了一种肾小管内压力振荡反应,其可能起源于血管,对远端肾小管液体输送的微小生理变化敏感。这种振荡显然表明正在进行血管阻力的调节,但目前它既未揭示效应位点(入球和/或出球小动脉),也未揭示效应机制(血管收缩和/或扩张)。肾素 - 血管紧张素系统似乎参与了这一现象。

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