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门静脉高压症和食管静脉曲张的外科治疗。十年经验。

Surgical management of portal hypertension and esophageal varices. 10 year experience.

作者信息

Vogt D P, Santoscoy T, Cooperman A M, Hermann R E

出版信息

Am J Surg. 1983 Aug;146(2):274-9. doi: 10.1016/0002-9610(83)90390-2.

Abstract

The results of 157 operations performed for portal hypertension and esophageal varices on 148 patients at the Cleveland Clinic in the 10 year period between 1970 and 1980 are reported. One hundred four shunt procedures and 53 ligation procedures were performed. The overall operative mortality rate of 13 percent did not differ significantly from the 11 percent rate reported from this institution in 1971. A comparatively higher rate of recurrent variceal hemorrhage and a lower rate of encephalopathy reflected our increased use of selective shunts and ligation procedures. There was no improvement in overall long-term survival, which was approximately 50 percent. The two most important factors in predicting the results of all operations for esophageal varices continue to be assessment of preoperative liver function and the timing of the operation. The best results were obtained in patients with good liver function who had an elective operation. Our data suggest that the portacaval shunt is associated with a higher incidence of late mortality, largely as a result of liver failure; therefore, our preference now is to perform a distal selective splenorenal shunt procedure whenever possible. If a selective shunt procedure cannot be performed, we advocate either a mesocaval shunt or a ligation procedure, depending on patient risk and the suitability of veins for a shunt procedure.

摘要

报告了1970年至1980年这10年间在克利夫兰诊所对148例患者进行的157次门静脉高压症和食管静脉曲张手术的结果。共进行了104次分流手术和53次结扎手术。13%的总体手术死亡率与该机构1971年报告的11%的死亡率没有显著差异。相对较高的曲张静脉再出血率和较低的脑病发生率反映了我们对选择性分流术和结扎术的使用增加。总体长期生存率没有改善,约为50%。预测所有食管静脉曲张手术结果的两个最重要因素仍然是术前肝功能评估和手术时机。肝功能良好且接受择期手术的患者取得了最佳结果。我们的数据表明,门腔分流术与较高的晚期死亡率相关,主要是由于肝功能衰竭;因此,我们现在的首选是尽可能进行远端选择性脾肾分流术。如果无法进行选择性分流术,我们主张根据患者风险和静脉是否适合分流术进行肠系膜上腔静脉分流术或结扎术。

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