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[门静脉高压症的多学科管理:门体分流手术的现状]

[Interdisciplinary management of portal hypertension: status of portosystemic shunt operations].

作者信息

Häring R

出版信息

Zentralbl Chir. 1995;120(2):95-102.

PMID:7709669
Abstract

Decompressive portosystemic shunt operations continue to be part of the therapeutic concept for hemorhaging of esophageal varices inspite of endoscopic scelerotherapy and TIPS. Discussion of the different surgical indications, in particular for the emergency shunt. Analysis of our own patients. From 1970-1992 we saw 928 patients with bleeding varices, 755 operations were performed due to variceal bleeding, of these 686 portosystemic shunts and 69 disconnection operations. In 546 (79.5%) patients a portocaval anastomosis was performed, of which 356 (65.2%) being emergency or early operations and 190 (34.8%) elective operations. The mortality, dependent on the degree of hemorrhaging and the number of previous recurrent bleedings, could be drastically reduced inspite of a broad indication: to 33% in emergency shunts, to 6% in elective shunts, to 0% in stage Child A since 1980. In stage Child C, the Warren shunt is preferred. The rate of encephalopathy: 12% latent and reversible, 12% chronic (alcoholics). Late mortality is dependent on the status of liver cirrhosis and on alcohol abstinence. The 5- and 10-year expected survival rates are 72% or 39% in abstinent patients, and in non-abstinent patients 36% or 0%, respectively.

摘要

尽管有内镜硬化疗法和经颈静脉肝内门体分流术(TIPS),减压性门体分流手术仍是食管静脉曲张出血治疗理念的一部分。讨论不同的手术适应症,尤其是急诊分流术。分析我们自己的患者。1970年至1992年,我们共诊治928例静脉曲张出血患者,因静脉曲张出血进行了755例手术,其中686例为门体分流术,69例为断流术。546例(79.5%)患者进行了门腔静脉吻合术,其中356例(65.2%)为急诊或早期手术,190例(34.8%)为择期手术。尽管适应症广泛,但死亡率仍可大幅降低:急诊分流术的死亡率降至33%,择期分流术的死亡率降至6%,自1980年以来,Child A期患者的死亡率降至0%。在Child C期,首选Warren分流术。肝性脑病发生率:潜在可逆性为12%,慢性(酗酒者)为12%。晚期死亡率取决于肝硬化状况和戒酒情况。戒酒患者的5年和10年预期生存率分别为72%和39%,未戒酒患者分别为36%和0%。

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