Moilanen T, Nikkari T, Räsänen L, Viikari J, Akerblom H K, Ahola M, Dahl M, Lähde P L, Pesonen E, Pietikäinen M, Seppänen A, Suoninen P, Uhari M
Atherosclerosis. 1983 Jul;48(1):49-56. doi: 10.1016/0021-9150(83)90016-3.
Risk factors associated with coronary heart disease were surveyed in a multicentre study carried out in 1979 among children living in different parts of Finland. The survey included analyses of plasma lipids and cholesteryl ester (CE) fatty acids as well as a dietary interview by a 48-hour recall method. The present report gives the plasma fatty acid compositions obtained from 181 3-year-old and 226 12-year-old children and their relations to dietary factors and other plasma lipids. The mean percentages (+/- SD) of CE linoleate in the 3- and 12-year-old children were 49.2 +/- 5.2 and 5.10 +/- 51.0%, respectively. Differences in CE fatty acid composition between the various regions of Finland were relatively small, but there was a trend to higher proportions of polyunsaturated fatty acids in western and urban compared with eastern and rural communities. Among different dietary constituents the daily intake of margarine + oils or butter had the greatest effect on plasma CE fatty acid composition. There was a highly significant positive correlation between the dietary P/S ratio and the percentage of CE linoleate in plasma.
1979年,在芬兰不同地区的儿童中开展了一项多中心研究,调查与冠心病相关的危险因素。该调查包括对血浆脂质和胆固醇酯(CE)脂肪酸的分析,以及采用48小时回忆法进行的饮食访谈。本报告给出了从181名3岁儿童和226名12岁儿童中获得的血浆脂肪酸组成,以及它们与饮食因素和其他血浆脂质的关系。3岁和12岁儿童中CE亚油酸的平均百分比(±标准差)分别为49.2±5.2和51.0±5.10%。芬兰不同地区之间CE脂肪酸组成的差异相对较小,但与东部和农村社区相比,西部和城市社区中多不饱和脂肪酸的比例有升高趋势。在不同的饮食成分中,人造黄油+油或黄油的每日摄入量对血浆CE脂肪酸组成的影响最大。饮食中的P/S比值与血浆中CE亚油酸的百分比之间存在高度显著的正相关。