Zauli C, Murialdo G, Piscopo R, Gatti M, Calzia R, Giovale M
Boll Soc Ital Biol Sper. 1983 Apr 30;59(4):455-61.
The 24-hour periodicity of PRL secretion in 7 prolactinoma subjects of both sexes has been studied by means of the Fourier's harmonic analysis. In all cases elevated PRL titres have been found, that did not show the physiological changes due to sleep and wake. In most of the cases could not be demonstrated either a significant secretory periodicity or secretory episodes occurred with a frequency higher than in the control groups. Such secretory features may depend on changes in the neoplastic cells' receptors for regulating neurotransmitters.
通过傅里叶谐波分析研究了7名男女催乳素瘤患者催乳素（PRL）分泌的24小时周期性。在所有病例中均发现PRL水平升高，且未显示出因睡眠和觉醒引起的生理变化。在大多数病例中，既未证明存在明显的分泌周期性，也未发现分泌发作频率高于对照组。这种分泌特征可能取决于肿瘤细胞中调节神经递质的受体的变化。
