Calzia R, Giovale M, Murialdo G, Piscopo R, Santoni O, Zauli C
Boll Soc Ital Biol Sper. 1982 May 15;58(9):539-45.
PRL levels over 24 hours have been studied in 9 acromegalic patients (4 men and 4 women). Hormone levels were found significantly higher than age and sex matched normal subjects in 4 cases (2 males and 2 females). PRL and STH levels were significantly correlated in men, but not in women. A 24-hour periodicity of PRL secretion was found in 4 cases, however in 2 of them the phase was anticipated in respect to the control group. In 4 of the remaining subjects the hormone secretion is made up by a succession of episodes with higher frequency than in the control group. Only in one case no significant periodicity of secretion was observed.
对9例肢端肥大症患者（4例男性，4例女性）的催乳素（PRL）水平进行了24小时监测。发现4例患者（2例男性，2例女性）的激素水平显著高于年龄和性别匹配的正常受试者。男性的PRL和生长激素（STH）水平显著相关，而女性则不然。4例患者发现有PRL分泌的24小时周期性，然而其中2例相对于对照组其周期提前。其余受试者中有4例激素分泌由一系列发作组成，发作频率高于对照组。仅1例未观察到明显的分泌周期性。
