Bagnoli F, Vispi L, Buonocore G, Bruchi S, Sardelli S, Cusi G
Boll Soc Ital Biol Sper. 1983 Jun 30;59(6):870-5.
Two groups of newborns on different diets were studied: group A was given artificial milk, while group B was breast fed. Blood samples from the cord artery and vein were taken at birth and further blood samples after 1, 6, 12, 24, 48, 72, 96 and 168 hours. No baby underwent more than three blood samples. Calcium (Ca), magnesium (Mg), phosphorus (P) and parathormone (PTH) were measured in all samples. There was a rapid increase in PTH levels in all subjects in the first hours after birth. At 48th the babies in group A had significantly higher serum levels of P than the group B subjects, and their serum Ca and Mg levels were significantly lower. At 72th PTH serum levels were significantly higher in group A, while Ca and Mg levels were significantly higher in group B. In conclusion, the subjects demonstrated a normal secretion of PTH at birth, and the type of diet notably influenced the homeostasis of calcium in the perinatal period.
A组喂食人工奶粉，而B组采用母乳喂养。在出生时采集脐动脉和脐静脉的血样，并在出生后1、6、12、24、48、72、96和168小时采集更多血样。没有婴儿接受超过三次血样采集。对所有样本测量钙（Ca）、镁（Mg）、磷（P）和甲状旁腺激素（PTH）。出生后的最初几个小时内，所有受试者的PTH水平迅速升高。在第48小时，A组婴儿的血清P水平显著高于B组受试者，而其血清Ca和Mg水平显著较低。在第72小时，A组的PTH血清水平显著较高，而B组的Ca和Mg水平显著较高。总之，受试者在出生时表现出PTH的正常分泌，并且饮食类型显著影响围产期钙的稳态。
