Pabst R, Kamran D
Br J Exp Pathol. 1983 Jun;64(3):293-7.
In minipigs 1 ureter was replaced by a loop of the terminal ileum and the contralateral kidney removed. After 2.5 to 3 years the morphology of the replaced ureter was compared with the normal ileum. Independent of the 3 different operative techniques used, in about half of the pigs there was loss or flattening of the villi. In the other pigs the morphometrically determined number of intraepithelial lymphocytes, the cell density in the lamina propria and the length of the villi did not differ significantly compared with the normal ileum. There was no increase in goblet cells in the crypts. The transitional epithelium covered only a short distance at the anastomotic junctions. Peyer's patches of normal age-related size were found in the replaced ureter. Despite the long-term contact with urine instead of gut contents, in many pigs a normal amount of lymphocytes remained in the "ileal ureter".
在小型猪中，一条输尿管被一段回肠末端所替代，对侧肾脏被切除。2.5至3年后，将替代输尿管的形态与正常回肠进行比较。无论采用三种不同手术技术中的哪一种，约一半的猪出现绒毛缺失或变平。在其他猪中，经形态计量学测定的上皮内淋巴细胞数量、固有层细胞密度和绒毛长度与正常回肠相比无显著差异。隐窝中的杯状细胞没有增加。移行上皮仅在吻合处覆盖较短距离。在替代输尿管中发现了正常年龄相关大小的派尔集合淋巴结。尽管长期接触尿液而非肠内容物，但在许多猪中，“回肠输尿管”中仍保留了正常数量的淋巴细胞。
