Hunyady L, Balla T, Spät A
Biochim Biophys Acta. 1983 Aug 29;753(1):133-5. doi: 10.1016/0005-2760(83)90107-8.
Angiotensin II enhances phosphatidylinositol turnover in isolated adrenal glomerulosa cells. In the present experiments we examined whether this effect required the presence of extracellular Ca2+. It was found that neither the stimulation of phosphatidylinositol breakdown nor the stimulation of incorporation of [32P]phosphate into phosphatidic acid and phosphatidylinositol required the presence of extracellular Ca2+. These observations suggest that the enhancement of phosphatidylinositol turnover may precede, but does not depend on, angiotensin-induced Ca2+ influx.
血管紧张素II可增强分离的肾上腺球状带细胞中的磷脂酰肌醇周转率。在本实验中，我们研究了这种效应是否需要细胞外Ca2+的存在。结果发现，无论是刺激磷脂酰肌醇分解，还是刺激[32P]磷酸盐掺入磷脂酸和磷脂酰肌醇，均不需要细胞外Ca2+的存在。这些观察结果表明，磷脂酰肌醇周转率的增强可能先于血管紧张素诱导的Ca2+内流，但并不依赖于它。
