Chesnokova V M, Ivanova L N, Gruntenko E V
Biull Eksp Biol Med. 1983 Aug;96(8):89-91.
Congenitally athymic (nude) mice show significant disorders of endocrine functions of the gonads and adrenals. Transplantation of the thymus to such animals in the first days of life entails the normalization of the functions of the adrenals and testes but not of the ovaries in adult animals. It is inferred that abnormalities in the functions of the testes and adrenals in nude mice are consequent on the lack of the thymus in the early stages of ontogenesis.
先天性无胸腺(裸)小鼠表现出性腺和肾上腺内分泌功能的显著紊乱。在出生后的头几天将胸腺移植到这类动物体内,可使成年动物的肾上腺和睾丸功能恢复正常,但卵巢功能不能恢复正常。由此推断,裸鼠睾丸和肾上腺功能异常是由于个体发育早期缺乏胸腺所致。