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[胸腺对小鼠性腺和肾上腺内分泌功能的影响]

[Influence of the thymus on the endocrine function of the gonads and adrenals in mice].

作者信息

Chesnokova V M, Ivanova L N, Gruntenko E V

出版信息

Biull Eksp Biol Med. 1983 Aug;96(8):89-91.

PMID:6882912
Abstract

Congenitally athymic (nude) mice show significant disorders of endocrine functions of the gonads and adrenals. Transplantation of the thymus to such animals in the first days of life entails the normalization of the functions of the adrenals and testes but not of the ovaries in adult animals. It is inferred that abnormalities in the functions of the testes and adrenals in nude mice are consequent on the lack of the thymus in the early stages of ontogenesis.

摘要

先天性无胸腺(裸)小鼠表现出性腺和肾上腺内分泌功能的显著紊乱。在出生后的头几天将胸腺移植到这类动物体内,可使成年动物的肾上腺和睾丸功能恢复正常,但卵巢功能不能恢复正常。由此推断,裸鼠睾丸和肾上腺功能异常是由于个体发育早期缺乏胸腺所致。

相似文献

1
[Influence of the thymus on the endocrine function of the gonads and adrenals in mice].[胸腺对小鼠性腺和肾上腺内分泌功能的影响]
Biull Eksp Biol Med. 1983 Aug;96(8):89-91.
2
Evidence for thymus involvement in development of adrenal and gonadal endocrine functions in mice.胸腺参与小鼠肾上腺和性腺内分泌功能发育的证据。
Endocrinol Exp. 1987 Jun;21(2):133-42.
3
[Endocrine function of gonads and adrenal glands in athymic and thymectomized mice].[无胸腺和胸腺切除小鼠性腺与肾上腺的内分泌功能]
Biull Eksp Biol Med. 1982 Mar;93(3):102-4.
4
Role of the thymus in programming of neuroendocrine functions.胸腺在神经内分泌功能编程中的作用。
Clin Exp Immunol. 1975 May;20(2):323-38.
5
[Effect of thymosin (fraction 5) on the development of functional activity of the adrenals and gonads in genetically athymic mice].[胸腺素(5组分)对遗传性无胸腺小鼠肾上腺和性腺功能活性发育的影响]
Probl Endokrinol (Mosk). 1988 Nov-Dec;34(6):83-6.
6
The morphology of the endocrine system in congenitally athymic (nude) mice.先天性无胸腺(裸)小鼠内分泌系统的形态学
J Pathol. 1977 Apr;121(4):225-31. doi: 10.1002/path.1711210406.
7
[Problems in the genetics of stress. II. Genetic analysis of endocrine gland weight in mice under normal conditions and during exposure to stress].[应激遗传学中的问题。II. 正常条件下及应激暴露期间小鼠内分泌腺重量的遗传分析]
Genetika. 1976;12(12):72-80.
8
[Sex-related differences in blood and gonad levels of testosterone in silver fox fetuses].
Ontogenez. 2001 Jul-Aug;32(4):277-82.
9
The adrenals and gonads of congenitally thymusless nude mice.先天性无胸腺裸鼠的肾上腺和性腺。
J Endocrinol. 1973 Jul;58(1):vii.
10
[Influence of the gonads and adrenals on the induction of tryptophan pyrrolase with hydrocortisone in the rat].[性腺和肾上腺对大鼠体内氢化可的松诱导色氨酸吡咯酶的影响]
Arzneimittelforschung. 1974 Mar;24(3):330-3.

引用本文的文献

1
Influence of thymosin on the formation of the functional activity of the adrenals in mice.胸腺素对小鼠肾上腺功能活性形成的影响。
Neurosci Behav Physiol. 1987 Jul-Aug;17(4):353-7. doi: 10.1007/BF01183067.