Lee J Y, Breaux S R
Cancer. 1983 Sep 15;52(6):1014-6. doi: 10.1002/1097-0142(19830915)52:6<1014::aid-cncr2820520614>3.0.co;2-j.
Recruitment of patients to clinical trials is a multi-stage process. To participate in a protocol, a patient must meet all the eligibility requirements; the physicians managing the patient must be amenable to enrolling the patient on protocol; and finally, the patient must consent to participate. In 1979, 64 clinical trials were open to patient accrual in the Division of Radiation Oncology, Mallinckrodt Institute of Radiology, St. Louis, Missouri. A total of 1103 cases were reviewed. Two hundred sixty-three patients were eligible for one of the protocols, of whom 124 were successfully recruited. The reasons for ineligibility and nonparticipation are discussed.
患者进入临床试验是一个多阶段的过程。要参与一项方案，患者必须满足所有入选标准；负责该患者的医生必须愿意让患者按方案入组；最后，患者必须同意参与。1979年，密苏里州圣路易斯市马林克罗特放射研究所放射肿瘤学部有64项临床试验可供患者入组。共审查了1103例病例。263名患者符合其中一项方案的入选标准，其中124名成功入组。本文讨论了不符合入选标准和未参与的原因。
