Poppema S, van Voorst Vader P C, Rozeboom-Uiterwijk T, Dijkstra J W
Cancer. 1983 Oct 1;52(7):1178-82. doi: 10.1002/1097-0142(19831001)52:7<1178::aid-cncr2820520709>3.0.co;2-j.
A patient with "classical" lymphomatoid papulosis is described in whom self-healing tumorous lesions occurred. Histologic, immunologic, enzyme histochemical and ultrastructural studies were performed. The atypical cells were found to be of monocyte-macrophage origin. The infiltrate also contained a variable number of suppressor-cytotoxic T-lymphocytes, depending on the stage of the tumorous lesions. The number of IgA positive B-lymphocytes in the peripheral blood was increased. The findings indicate that "classical" lymphomatoid papulosis is not a cutaneous T-cell lymphoma, but is the expression of an abnormal, immune reaction in the skin.
描述了一名患有“经典型”淋巴瘤样丘疹病的患者，其出现了自愈性肿瘤性病变。进行了组织学、免疫学、酶组织化学和超微结构研究。发现非典型细胞起源于单核细胞-巨噬细胞。根据肿瘤性病变的阶段，浸润物中还含有数量不等的抑制性-细胞毒性T淋巴细胞。外周血中IgA阳性B淋巴细胞数量增加。这些发现表明，“经典型”淋巴瘤样丘疹病不是皮肤T细胞淋巴瘤，而是皮肤异常免疫反应的表现。
