Morphometric ultrastructural study of the regeneration of soleus muscle in hypokinesia.

The aim of the present study was a morphometric ultrastructural evaluation of regenerating soleus muscle fibers after denervation under conditions of hypokinesia. It was found that in rats kept under conditions of hypokinesia degenerative changes in the soleus muscle after denervation are more pronounced than in the control. On the 36th day after denervation of muscle, symptoms of regeneration of muscle fibers were observed. It was more pronounced in the control than in the experimental groups. Denervation and immobilization applied simultaneously causes more severe degeneration and atrophy of muscle fibers than does the action of only one of these factors.